High-resolution MADGE

Elimination of dumbbell bands and enhancement of resolution in MADGE using delayed start electrophoresis.

Microplate array diagonal gel electrophoresis (MADGE) is a highthroughput electrophoresis system that enables the simultaneous assay of many samples for known mutations (1,2). Problems noted often in electrophoresis include the distortion of the bands into dumbbell shapes sometimes with streaking or skiing down the sides of the gel track (Reference 5 and Figure 1). Uneven heating of the gel can...

Implantable Microsystems for High-Resolution Interfacing to the Brain

High-Resolution HLA-A Typing in Normal Iranian Population

Background: Human leukocyte antigen (HLA) gene is a highly polymorphic region. HLA typing is required to match patients and donors for transplantation; therefore, development of HLA registries is necessary for finding HLA match donors. HLA system is highly informative, and numerous studies have been conducted on HLA allele distribution in different populations. Methods: In this study,...

Classification of Ultra-high Resolution Images using Soft Computing

The main objective of this paper is to use a computational intelligence algorithm for preparing a mapping map that categorizes different patterns of identification of infected areas and changes in radiation pollution. In this paper, the use of the fuzzy inference system has been proposed to determine the degree of radiation contamination in the regions. The study uses ultra-high resolution spec...

MADGE: scalable distributed data management software for cDNA microarrays

MOTIVATION The human genome project and the development of new high-throughput technologies have created unparalleled opportunities to study the mechanism of diseases, monitor the disease progression and evaluate effective therapies. Gene expression profiling is a critical tool to accomplish these goals. The use of nucleic acid microarrays to assess the gene expression of thousands of genes sim...